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OVID-19 PCR Test protocol, Sensitivity, Specificity and therefore Operational False Positive Rate, and how the official figures are corrected for this

Jonathan Dench made this Freedom of Information request to Cabinet Office

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Dear Cabinet Office,

I have some strong scientific concern about COVID-19 testing and the handling of data by the UK Government.

Firstly no-specificity or sensitivity is provided which is completely unacceptable. It appears data is not being corrected for the Operational false positive rate of such tests. Current estimates of specificity from the literature are 95-99% ,this does not sound alarming at first, but once you account for test frequency and prevalence this is quite alarming, as it would provide an operational false positive rate of 90%. This can be confirmed from "with COVID death' data ie died within 28 days of positive PCR. If you compare current excess death with the average of the past 5 years with the governments estimates of COVID death, you get an Operational false positive rate of 70% for a sample with the highest pre-test probability of having COVID and therefore the lowest OFPR. This means the government statistics are meaningless without correction. This also means no mass indescriminate testing should take place as this would further worsen this problem. You should be doing a full investigation on this matter, as the Government draws us further into a pseudo pandemic.

What I am requesting:

Full PCR test protocol
Test sensitivity
Test specificity
How data is being corrected for Operational false positive rate.

If you cannot provide these then you should not be using PCR as a diagnostic test and a full investigation should be launched immediately.

Yours faithfully,

Dr Jonathan Dench

Yours faithfully,

Jonathan Dench

Cabinet Office FOI Team,

Our ref: FOI2020/21836

Dear JONATHAN DENCH,

Thank you for your request for information which was received on
22/12/2020. Your request is being handled under the terms of the Freedom
of Information Act 2000 ('the Act').

The Act requires that a response must be given promptly, and in any event
within 20 working days. We will therefore aim to reply at the latest by
25/1/2021.

Please remember to quote the reference number above in any future
communications.

Yours sincerely,

Freedom of Information Team

Cabinet Office

FOI Team Mailbox, Cabinet Office

1 Attachment

Please find attached the reply to your FOI request

 

 

 

Regards

 

 

FOI Team

Room 405

70 Whitehall,

London, SW1A 2AS

E-mail -[1][Cabinet Office request email] 

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Dear Cabinet Office,

Please pass this on to the person who conducts Freedom of Information reviews.

I am writing to request an internal review of Cabinet Office's handling of my FOI request 'OVID-19 PCR Test protocol, Sensitivity, Specificity and therefore Operational False Positive Rate, and how the official figures are corrected for this'.

The fact that you do not hold information on this means that you are unable to fulfil your requirement of making decisions on this matter. This is criminally unacceptable. Especially when Matt Hancock and Priti Patel are blaming the people of this country for this mess. Unfortunately it is unequivocally the fault of our leadership. I want a full review on why the cabinet office, is insisting on not undertaking their duty to ensure that the data science and management are undertaken with the rigor the public deserve.

Kind Regards,

Jonathan.

[ GIVE DETAILS ABOUT YOUR COMPLAINT HERE ]

A full history of my FOI request and all correspondence is available on the Internet at this address: https://www.whatdotheyknow.com/request/o...

Yours faithfully,

Jonathan Dench

Cabinet Office FOI Team,

Dear Jonathan Dench,

Thank you for your request for an internal review (reference
IR2021/01611), which was prompted by our response to your request for
information under the Freedom of Information Act 2000.

We shall endeavour to complete the internal review and respond to you
within 20 working days.

Please remember to quote the reference number above in any future
communications.

Yours sincerely,

FOI Team

Cabinet Office FOI Team,

1 Attachment

Dear Jonathan Dench,

Please find attached our response to your request for an Internal Review
(reference IR2021/01611).

Yours sincerely,

FOI Team

We don't know whether the most recent response to this request contains information or not – if you are Jonathan Dench please sign in and let everyone know.