Cost/Benefit Analysis of Primate Research

Gwrthodwyd y cais gan University of Cambridge.

Freedom of Information Act 2000 – Cost/Benefit Analysis of Primate Research

To Whom It May Concern,

I write in accordance with the Freedom of Information Act 2000 ("The Act") to request the disclosure of data held concerning the use of primates in research. For the purposes of clarification, 'research' is defined as any activity which falls within the Animal (Scientific Procedures) Act 1986 ("ASPA").

The information I wish to request is as follows:

1. The cost/benefit analysis for the following primate research projects:

a. Opposing Effects of 5,7-DHT Infusions into the Orbitofrontal Cortex and Amygdala on Flexible Responding - Cerebral Cortex, July 2010;20:1668—1675

b. Autonomic, Behavioral, and Neural Analyses of Mild Conditioned Negative Affect in Marmosets - Behavioral Neuroscience, 2010, Vol. 124, No. 2, 192–203

c. Differential Contributions of the Primate Ventrolateral Prefrontal and Orbitofrontal Cortex to Serial Reversal Learning - The Journal of Neuroscience, October 27, 2010; 30(43):14552–14559

d. Contribution of the amygdala, but not orbitofrontal or medial prefrontal cortices, to the expression of flavour preferences in marmoset monkeys - European Journal of Neuroscience, Vol. 34, pp. 1006–1017, 2011

e. Dopamine, But Not Serotonin, Regulates Reversal Learning in the Marmoset Caudate Nucleus - The Journal of Neuroscience, March 16, 2011; 31(11):4290–4297

f. Lesions of Ventrolateral Prefrontal or Anterior Orbitofrontal Cortex in Primates Heighten Negative Emotion – Biological Psychiatry, Volume 72, Issue 4, Pages 266 – 272 (August 2012)

g. Adaptation of Reward Sensitivity in Orbitofrontal Neurons - The Journal of Neuroscience, January 13, 2010; 30(2):534 –544

h. Convergence of Pyramidal and Medial Brain Stem Descending Pathways Onto Macaque Cervical Spinal Interneurons - J Neurophysiol 103:2821-2832, 2010

i. Coding of Reward Risk by Orbitofrontal Neurons Is Mostly Distinct from Coding of Reward Value – Neuron, Volume 68, Issue 4, 789-800, 18 November 2010

j. A Bayesian Approach to Analyse Genetic Variation within RNA Viral Populations – (2011) A Bayesian Approach to Analyse Genetic Variation within RNA Viral Populations. PLoS Comput Biol 7(3)

k. Sensitivity to Temporal Reward Structure in Amygdala Neurons - Current Biology, Volume 22, Issue 19, 1839-1844, 06 September 2012

l. Prediction of economic choice by primate amygdala neurons - Cerebral Cortex; 11/2009; 20(7):1668-75

I must stress that I am not interested in data which identifies those under the employ of the institution or any third parties and wholly agree for such personal information to be redacted or the identities of persons to be concealed.

As I am sure you are aware, The Act dictates that a response must
be given within 20 days of receipt of this request. In the eventuality of any delay, I request that you keep me informed. If there are any matters on which you seek clarity, please do not hesitate to contact me.

Many thanks for your assistance and time spent in handling my request.

Kind Regards,

Luke Steele

FOI, University of Cambridge

Dear Mr Steele,

This is to acknowledge receipt of your request for information. Your reference number is FOI-2013-307. We will respond on or before 28 October 2013.

Regards,
FOI Team

Freedom of Information Office
University of Cambridge
Registrary's Office, The Old Schools
Trinity Lane, Cambridge, CB2 1TN
T: (01223 7)64142
F: (01223 3)32332
E: [email address]

dangos adrannau a ddyfynnir

FOI, University of Cambridge

1 Atodiad

Dear Mr Steele,

Further to your request for information, please find attached the University’s response.

Regards,
FOI Team

Freedom of Information Office
University of Cambridge
Registrary's Office, The Old Schools
Trinity Lane, Cambridge, CB2 1TN
T: (01223 7)64142
F: (01223 3)32332
E: [email address]

dangos adrannau a ddyfynnir