Dear Imperial College London,

To build a picture of your adhesion to the EU registry requirements as part of ongoing research into university clinical trial transparency for UAEM, we have questions regarding your transparency on clinical trials.

Imperial College are currently being out-performed by many other top UK research institutions in terms of published data on clinical trials. At present, only 58.8% of due trial results have been published. As students, we demand greater transparency from our university, considering the impact of, and trust in, Imperial's medical research worldwide.

1) Are all Imperial College clinical trials registered to an online database?
2) Is trial 2014-004112-11 published anywhere?
3) Will the results of trial 2013-003196-35 be updated on the EU clinical trial register?
4) Will the results of trial 2013-003196-35 be updated on the EU clinical trial register?
5) Are the final results of trial 2012-002357-35 published anywhere?
6) Is trial 2012-002199-15 published anywhere?
7) Will the results of trial 2011-001148-31 be updated on the EU clinical trial register?
8) Is trial 2011-000454-32 published anywhere?
9) Is trial 2010-020440-35 published anywhere?
10) Is trial 2009-012424-87 published anywhere?
11) Is trial 2008-005924-97 published anywhere?
12) Is trial 2008-004740-36 published anywhere?
13) Is trial 2008-004229-40 published anywhere?
14) How many of your clinical trials are falsely listed as ongoing?
15) Do you plan on signing the WHO Joint Statement on Public Disclosure of Results from Clinical Trials?
16) Have you finished setting up the Ethics and Integrity Team mentioned in your response to Till Bruckners FOI from 2018?(https://www.whatdotheyknow.com/request/c...)
Many thanks in advance for your prompt response.

Yours faithfully,

Florence Rodgers
Representative of UAEM Imperial College London

IMPFOI, Imperial College London

Dear Ms Rodgers,

This is to acknowledge receipt of your request below, made under the Freedom of Information Act. The College will respond to your request by 16 January 2020.

Yours,

Freedom of Information Team
Imperial College London 

dangos adrannau a ddyfynnir

Hunt, Anita, Imperial College London

Dear Ms Rodgers,

 

Thank you for your Freedom of Information Act request. We have copied your
queries and provided the College’s response to each one as follows:

 

1) Are all Imperial College clinical trials registered to an online
database? ​

 

All Imperial College sponsored clinical trials have to be registered as a
condition of sponsorship approval. 

 

2) Is trial 2014-004112-11 published anywhere? 

 

It is registered on ClinicalTrials.gov (NCT02681523), but does not have
results posted. The PI has been asked to upload the results as soon as
possible.

 

3) Will the results of trial 2013-003196-35 be updated on the EU clinical
trial register? 

 

The results were posted on the EudraCT website on Dec 18 2019. However, it
often takes a few weeks for the results to show up on EudraCT after they
have been submitted, while the website reviews. The study has two
publications, their PubMed ID: 29119217, 29030624.

 

4) Will the results of trial 2013-003196-35 be updated on the EU clinical
trial register? 

 

See above answer

 

5) Are the final results of trial 2012-002357-35 published anywhere? 

 

Results were posted on the EudraCT website on Dec 13 2019.

 

6) Is trial 2012-002199-15 published anywhere? 

 

The results were posted on the EudraCT website on Nov 27 2019 and on
ClinicalTrials.gov (NCT02305940) on Dec 4 2019.

 

 7) Will the results of trial 2011-001148-31 be updated on the EU clinical
trial register? 

 

The trial results have been updated by the Research Integrity Officer on
EudraCT and ClinicalTrials.gov (NCT01539837) in draft form and the
researcher has been asked to confirm the information is correct. Once that
confirmation is obtained, the results will be posted. Results published in
journal, PubMed ID:  28469157.

 

8) Is trial 2011-000454-32 published anywhere? 

 

The researcher anticipates being able to post the results in January of
2020.

 

9) Is trial 2010-020440-35 published anywhere?

 

No. Results have been uploaded to ClinicalTrials.gov (NCT01787097) but
comments and corrections need to be responded to by the PI before the
results will be available to the public. Once the ClinicalTrials.gov entry
is completed, the EudraCT entry will be updated.

 

10) Is trial 2009-012424-87 published anywhere? 

 

Results were submitted to EudraCT on Dec 11 2019.

 

11) Is trial 2008-005924-97 published anywhere? 

 

Results posted on EudraCT on Dec 17 2019.

 

12) Is trial 2008-004740-36 published anywhere? 

 

The PI has been asked to publish.

 

13) Is trial 2008-004229-40 published anywhere? 

 

Yes, results are available on ClinicalTrials.gov (NCT00944658).  Results
were submitted to EudraCT on Nov 18 2019 so should be available publicly
soon. There is also a journal publication, PubMed ID: 22984171. 

 

14) How many of your clinical trials are falsely listed as ongoing? ​

 

This is not information that is held by the College.

 

15) Do you plan on signing the WHO Joint Statement on Public Disclosure of
Results from Clinical Trials? ​

 

Imperial is currently signed up to the AllTrials campaign. 

 

16) Have you finished setting up the Ethics and Integrity Team mentioned
in your response to Till Bruckners FOI from 2018? 

 

​A dedicated Research Integrity Officer is now in place, and the JRCO is
in the final stages of restructuring to become the Research Governance and
Integrity team.

 

If you are unhappy with the way that we have handled your request, you can
ask us to conduct a review. Please make your representation in writing
within 40 days of the date you received this response. If you remain
dissatisfied with how Imperial College has handled your request, you may
then approach the [1]Information Commissioner’s Office.   

 

Yours,

 

Freedom of Information Team

[2]Imperial College London 

 

 

dangos adrannau a ddyfynnir