24 February 2008
File ref: T/3/7/101
Dr Geraint Bevan
Email:
request-6719-
[email address]
Dear Dr Bevan
Thank you for your email dated 26 January 2009, in which you asked for
details of research involving animal testing undertaken at the University of
Edinburgh, funded wholly or in part by cosmetics companies for each year
since 1997. I am pleased to provide the following information in response to
your request.
We have identified one research project which is partly funded by a cosmetic
company. The current project licence covering this work was awarded in
August 2005. The aims and benefits associated with the project can be found
in the attached document entitled ‘Cosmetic Company Funded Research –
Project Details’.
Copyright in the information you have been given belongs to the University of
Edinburgh or to another party. Copyright material must not be copied,
distributed, modified, reproduced, transmitted, published (including published
on the Internet or an intranet), or otherwise made available in whole or in part
without the prior written consent of the copyright holder.
Yours sincerely
Cosmetic Company Funded Research - February 2009
Funding details: In July 2008 the researcher won a “fellowship for women in science” which
was joint funded by L’Oreal and
United Nations Educational, Scientific and Cultural
Organization (UNESCO) and also involved the Royal Institution of Great Britain and the UK
Resource Centre for Women in Science, Engineering and Technology. This fellowship has
provided modest funds for the researcher’s work on malaria parasites.
Research aims: Malaria parasites cause some of the most serious infectious diseases of
humans, our livestock, companion animals and wildlife. There is a great deal of research into
the genetics, cell and molecular biology, and immunology of malaria parasites but despite this
effort, malaria parasites remain a step ahead of medical science. The researcher’s work takes
a broader view and considers how these parasites have evolved sophisticated strategies to
maximise their ability to infect mosquito vectors, which they must do to be able to be
transmitted to new hosts (infections). For example, malaria parasites have both an asexual-
and sexual phase. The asexual phase is responsible for causing the symptoms of disease,
but the sexual phase is responsible for transmitting parasites to mosquitoes. A large part of
the researcher’s work is motivated by the need to understand the sex and social lives of
parasites to help develop medical interventions to target them. Recently it has been
discovered that, after mating, some parasites undergo apoptosis (a form of programmed-cell-
suicide) inside mosquitoes, rather than infecting them. This seems to contradict ‘Darwinian
survival of the fittest’ as parasites are expected to evolve strategies to maximise their
proliferation not their death. The fellowship for women in science allows the researcher to
harness recently developed experimental techniques to investigate why parasites have
evolved to undergo apoptosis.
Expected benefits: Harnessing this suicide-like behaviour in parasites could offer a new
paradigm to treat infectious disease – and could apply to parasites that cause leishmaniasis
and sleeping sickness too – but requires an understanding of the evolution, physiology, and
genetics of this behaviour first. More generally, there is an increasing demand to be able to
use evolutionary principles to evaluate the likely short- and long-term success of medical
inventions. However, the success of this endeavor hinges on understanding whether the
basic biology of parasites can be explained by evolutionary theories.
Document Outline
- BevanResponseLetter20090220vii.doc
- Cosmetic Company Funded Research - Project Details.doc